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26.

256
Accesses

Research   Open Access Highly Accessed

Foetal testosterone and autistic traits in 18 to 24-month-old children

Bonnie Auyeung, Kevin Taylor, Gerald Hackett, Simon Baron-Cohen Molecular Autism 2010, 1:11 (12 July 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

Increased prenatal exposure to testosterone is associated with autistic traits in children aged 18 to 24 months and is consistent with positive correlations previously identified in older children and adults.

27.

230
Accesses

Short report   Open Access

Spatial localisation in autism: evidence for differences in early cortical visual processing

Keziah Latham, Susana TL Chung, Peter M Allen, Teresa Tavassoli, Simon Baron-Cohen Molecular Autism 2013, 4:4 (19 February 2013)

Abstract | Full text | PDF | PubMed

28.

226
Accesses

Research   Open Access Highly Accessed

Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication

Ozlem Bozdagi, Takeshi Sakurai, Danae Papapetrou, Xiaobin Wang, Dara L Dickstein, Nagahide Takahashi, Yuji Kajiwara, Mu Yang, Adam M Katz, Maria Scattoni, Mark J Harris, Roheeni Saxena, Jill L Silverman, Jacqueline N Crawley, Qiang Zhou, Patrick R Hof, Joseph D Buxbaum Molecular Autism 2010, 1:15 (17 December 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | F1000 Biology |  Editor’s summary

Recent discovery may explain how mutations affecting SHANK3 may lead to autism spectrum disorders

29.

218
Accesses

Research   Open Access Highly Accessed

An X chromosome-wide association study in autism families identifies TBL1X as a novel autism spectrum disorder candidate gene in males

Ren-Hua Chung, Deqiong Ma, Kai Wang, Dale J Hedges, James M Jaworski, John R Gilbert, Michael L Cuccaro, Harry H Wright, Ruth K Abramson, Ioanna Konidari, Patrice L Whitehead, Gerard D Schellenberg, Hakon Hakonarson, Jonathan L Haines, Margaret A Pericak-Vance, Eden R Martin Molecular Autism 2011, 2:18 (4 November 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

TBL1X, which is part of the Wnt signaling pathway, is identified as a candidate gene for autism spectrum disorder (ASD), in the largest chromosome-wide study of the X chromosome in association with ASD.

30.

216
Accesses

Research   Open Access

Elevated cortisol during play is associated with age and social engagement in children with autism

Blythe A Corbett, Clayton W Schupp, David Simon, Niles Ryan, Sally Mendoza Molecular Autism 2010, 1:13 (27 September 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

31.

215
Accesses

Research   Open Access

Brain region-specific altered expression and association of mitochondria-related genes in autism

Ayyappan Anitha, Kazuhiko Nakamura, Ismail Thanseem, Kazuo Yamada, Yoshimi Iwayama, Tomoko Toyota, Hideo Matsuzaki, Taishi Miyachi, Satoru Yamada, Masatsugu Tsujii, Kenji J Tsuchiya, Kaori Matsumoto, Yasuhide Iwata, Katsuaki Suzuki, Hironobu Ichikawa, Toshiro Sugiyama, Takeo Yoshikawa, Norio Mori Molecular Autism 2012, 3:12 (1 November 2012)

Abstract | Full text | PDF | PubMed

32.

215
Accesses

Research   Open Access

High-functioning autism spectrum disorder and fragile X syndrome: report of two affected sisters

Pauline Chaste, Catalina Betancur, Marion Gérard-Blanluet, Anne Bargiacchi, Suzanne Kuzbari, Séverine Drunat, Marion Leboyer, Thomas Bourgeron, Richard Delorme Molecular Autism 2012, 3:5 (27 June 2012)

Abstract | Full text | PDF | PubMed

33.

207
Accesses

Research   Open Access

Social and monetary reward processing in autism spectrum disorders

Sonja Delmonte, Joshua H Balsters, Jane McGrath, Jacqueline Fitzgerald, Sean Brennan, Andrew J Fagan, Louise Gallagher Molecular Autism 2012, 3:7 (26 September 2012)

Abstract | Full text | PDF | PubMed

34.

203
Accesses

Research   Open Access

A large-scale survey of the novel 15q24 microdeletion syndrome in autism spectrum disorders identifies an atypical deletion that narrows the critical region

L McInnes, Alisa Nakamine, Marion Pilorge, Tracy Brandt, Patricia Jiménez González, Marietha Fallas, Elina R Manghi, Lisa Edelmann, Joseph Glessner, Hakon Hakonarson, Catalina Betancur, Joseph D Buxbaum Molecular Autism 2010, 1:5 (19 March 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

35.

199
Accesses

Short report   Open Access

Variation in the autism candidate gene GABRB3 modulates tactile sensitivity in typically developing children

Teresa Tavassoli, Bonnie Auyeung, Laura C Murphy, Simon Baron-Cohen, Bhismadev Chakrabarti Molecular Autism 2012, 3:6 (6 July 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Novel human study shows an association between GABRB3 variation and tactile sensitivity, supporting previous evidence from animal models implicating the role of GABRB3 variation in the atypical sensory sensitivity in autism spectrum conditions.

36.

195
Accesses

Short report   Open Access

Failure to deactivate the default mode network indicates a possible endophenotype of autism

Michael D Spencer, Lindsay R Chura, Rosemary J Holt, John Suckling, Andrew J Calder, Edward T Bullmore, Simon Baron-Cohen Molecular Autism 2012, 3:15 (3 December 2012)

Abstract | Full text | PDF | PubMed

37.

183
Accesses

Research   Open Access

Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces

Bhismadev Chakrabarti, Simon Baron-Cohen Molecular Autism 2011, 2:10 (29 June 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Variations in the CNR1 gene are associated with how long people look at facial expression of emotion, particularly happy faces; these findings could lead to further understanding of clinical conditions marked by atypical eye contact and facial emotion processing such as autism.

38.

180
Accesses

Research   Open Access Highly Accessed

Evidence of novel fine-scale structural variation at autism spectrum disorder candidate loci

Dale J Hedges, Kara L Hamilton-Nelson, Stephanie J Sacharow, Laura Nations, Gary W Beecham, Zhanna M Kozhekbaeva, Brittany L Butler, Holly N Cukier, Patrice L Whitehead, Deqiong Ma, James M Jaworski, Lubov Nathanson, Joycelyn M Lee, Stephen L Hauser, Jorge R Oksenberg, Michael L Cuccaro, Jonathan L Haines, John R Gilbert, Margaret A Pericak-Vance Molecular Autism 2012, 3:2 (2 April 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Support for the role of rare structural variants at multiple genomic loci in autism spectrum disorders, and in particular the significant enrichment of rare exonic deletions in NRXN1 in autistic vs. non-autistic individuals.

39.

176
Accesses

Research   Open Access

Self-referential and social cognition in a case of autism and agenesis of the corpus callosum

Michael V Lombardo, Bhismadev Chakrabarti, Meng-Chuan Lai, MRC AIMS Consortium, Simon Baron-Cohen Molecular Autism 2012, 3:14 (21 November 2012)

Abstract | Full text | PDF | PubMed

40.

175
Accesses

Review   Open Access

A review of the evidence for the canonical Wnt pathway in autism spectrum disorders

Hans Kalkman Molecular Autism 2012, 3:10 (19 October 2012)

Abstract | Full text | PDF | PubMed

41.

170
Accesses

Research   Open Access

Paternal age increases the risk for autism in an Iranian population sample

Roksana Sasanfar, Stephen A Haddad, Ala Tolouei, Majid Ghadami, Dongmei Yu, Susan L Santangelo Molecular Autism 2010, 1:2 (22 February 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

42.

166
Accesses

Short report   Open Access

Immune function genes CD99L2, JARID2 and TPO show association with autism spectrum disorder

Paula S Ramos, Satria Sajuthi, Carl D Langefeld, Stephen J Walker Molecular Autism 2012, 3:4 (9 June 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

43.

165
Accesses

Research   Open Access

Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism

Sharifia Wills, Christy C Rossi, Jeffrey Bennett, Veronica Martinez-Cerdeño, Paul Ashwood, David G Amaral, Judy Van de Water Molecular Autism 2011, 2:5 (26 April 2011)

Abstract | Full text | PDF | PubMed

44.

158
Accesses

Short report   Open Access

Investigation of the serum levels of anterior pituitary hormones in male children with autism

Keiko Iwata, Hideo Matsuzaki, Taishi Miyachi, Chie Shimmura, Shiro Suda, Kenji J Tsuchiya, Kaori Matsumoto, Katsuaki Suzuki, Yasuhide Iwata, Kazuhiko Nakamura, Masatsugu Tsujii, Toshirou Sugiyama, Kohji Sato, Norio Mori Molecular Autism 2011, 2:16 (19 October 2011)

Abstract | Full text | PDF | PubMed

45.

157
Accesses

Research   Open Access

Functionality of promoter microsatellites of arginine vasopressin receptor 1A (AVPR1A): implications for autism

Katherine E Tansey, Matthew J Hill, Lynne E Cochrane, Michael Gill, Richard JL Anney, Louise Gallagher Molecular Autism 2011, 2:3 (31 March 2011)

Abstract | Full text | PDF | PubMed

46.

155
Accesses

Research   Open Access Highly Accessed

Polymorphisms in leucine-rich repeat genes are associated with autism spectrum disorder susceptibility in populations of European ancestry

Inês Sousa, Taane G Clark, Richard Holt, Alistair T Pagnamenta, Erik J Mulder, Ruud B Minderaa, Anthony J Bailey, Agatino Battaglia, Sabine M Klauck, Fritz Poustka, Anthony P Monaco, International Molecular Genetic Study of Autism Consortium (IMGSAC) Molecular Autism 2010, 1:7 (25 March 2010)

Abstract | Full text | PDF | PubMed

47.

155
Accesses

Research   Open Access

Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study

Paula E Goines, Lisa A Croen, Daniel Braunschweig, Cathleen K Yoshida, Judith Grether, Robin Hansen, Martin Kharrazi, Paul Ashwood, Judy Van de Water Molecular Autism 2011, 2:13 (2 August 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

48.

153
Accesses

Short report   Open Access

Optimizing the phenotyping of rodent ASD models: enrichment analysis of mouse and human neurobiological phenotypes associated with high-risk autism genes identifies morphological, electrophysiological, neurological, and behavioral features

Joseph D Buxbaum, Catalina Betancur, Ozlem Bozdagi, Nate P Dorr, Gregory A Elder, Patrick R Hof Molecular Autism 2012, 3:1 (20 February 2012)

Abstract | Full text | PDF | PubMed

49.

151
Accesses

Research   Open Access

Gene expression analysis in lymphoblasts derived from patients with autism spectrum disorder

Yuka Yasuda, Ryota Hashimoto, Hidenaga Yamamori, Kazutaka Ohi, Motoyuki Fukumoto, Satomi Umeda-Yano, Ikuko Mohri, Akira Ito, Masako Taniike, Masatoshi Takeda Molecular Autism 2011, 2:9 (26 May 2011)

Abstract | Full text | PDF | PubMed

50.

144
Accesses

Research   Open Access

Neuropathologic features in the hippocampus and cerebellum of three older men with fragile X syndrome

Claudia M Greco, Celestine S Navarro, Michael R Hunsaker, Izumi Maezawa, John F Shuler, Flora Tassone, Mary Delany, Jacky W Au, Robert F Berman, Lee-Way Jin, Cynthia Schumann, Paul J Hagerman, Randi J Hagerman Molecular Autism 2011, 2:2 (8 February 2011)

Abstract | Full text | PDF | PubMed

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