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1.

1400
Accesses

Editorial   Open Access

DSM-5: the debate continues

Joseph D Buxbaum, Simon Baron-Cohen Molecular Autism 2013, 4:11 (15 May 2013)

Abstract | Provisional PDF | PubMed |  Editor’s summary

Joseph Buxbaum and Simon Baron-Cohen comment on the debate surrounding the forthcoming edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5) and the potential implications of the new diagnostic criteria for the autism spectrum.

2.

1249
Accesses

Commentary   Open Access

Autism in DSM-5: progress and challenges

Fred R Volkmar, Brian Reichow Molecular Autism 2013, 4:13 (15 May 2013)

Abstract | Provisional PDF | PubMed

3.

1225
Accesses

Review   Open Access

DSM-5 and autism spectrum disorders (ASDs): an opportunity for identifying ASD subtypes

Rebecca Grzadzinski, Marisela Huerta, Catherine Lord Molecular Autism 2013, 4:12 (15 May 2013)

Abstract | Provisional PDF | PubMed

4.

1050
Accesses

Research   Open Access Highly Accessed

Common genetic variants, acting additively, are a major source of risk for autism

Lambertus Klei, Stephan J Sanders, Michael T Murtha, Vanessa Hus, Jennifer K Lowe, A Willsey, Daniel Moreno-De-Luca, Timothy W Yu, Eric Fombonne, Daniel Geschwind, Dorothy E Grice, David H Ledbetter, Catherine Lord, Shrikant M Mane, Christa Martin, Donna M Martin, Eric M Morrow, Christopher A Walsh, Nadine M Melhem, Pauline Chaste, James S Sutcliffe, Matthew W State, Edwin H Cook, Kathryn Roeder, Bernie Devlin Molecular Autism 2012, 3:9 (15 October 2012)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Common genetic variants have a substantial additive genetic effect on autism spectrum disorder liability and this effect differs between simplex and multiplex families.

5.

1014
Accesses

Short report   Open Access

Insulin-like growth factor-1 rescues synaptic and motor deficits in a mouse model of autism and developmental delay

Ozlem Bozdagi, Teresa Tavassoli, Joseph D Buxbaum Molecular Autism 2013, 4:9 (27 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

6.

969
Accesses

Research   Open Access Highly Accessed

Whole-genome sequencing in an autism multiplex family

Lingling Shi, Xu Zhang, Ryan Golhar, Frederick G Otieno, Mingze He, Cuiping Hou, Cecilia Kim, Brendan Keating, Gholson J Lyon, Kai Wang, Hakon Hakonarson Molecular Autism 2013, 4:8 (18 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

7.

947
Accesses

Letter to the Editor   Open Access

Sex-biased gene expression in the developing brain: implications for autism spectrum disorders

Mark N Ziats, Owen M Rennert Molecular Autism 2013, 4:10 (7 May 2013)

Abstract | Full text | PDF | ePUB | PubMed

8.

604
Accesses

Short report   Open Access Highly Accessed

PCR and serology find no association between xenotropic murine leukemia virus-related virus (XMRV) and autism

Brent C Satterfield, Rebecca A Garcia, Fiorella Gurrieri, Charles E Schwartz Molecular Autism 2010, 1:14 (14 October 2010)

Abstract | Full text | PDF | PubMed

9.

554
Accesses

Research   Open Access

Genome-wide identification of transcriptional targets of RORA reveals direct regulation of multiple genes associated with autism spectrum disorder

Tewarit Sarachana, Valerie W Hu Molecular Autism 2013, 4:14 (22 May 2013)

Abstract | Provisional PDF

10.

554
Accesses

Review   Open Access

Prevalence of autism in mainland China, Hong Kong and Taiwan: a systematic review and meta-analysis

Xiang Sun, Carrie Allison, Fiona E Matthews, Stephen J Sharp, Bonnie Auyeung, Simon Baron-Cohen, Carol Brayne Molecular Autism 2013, 4:7 (9 April 2013)

Abstract | Full text | PDF | ePUB | PubMed

11.

497
Accesses

Research   Open Access Highly Accessed

A noise-reduction GWAS analysis implicates altered regulation of neurite outgrowth and guidance in autism

John P Hussman, Ren-Hua Chung, Anthony J Griswold, James M Jaworski, Daria Salyakina, Deqiong Ma, Ioanna Konidari, Patrice L Whitehead, Jeffery M Vance, Eden R Martin, Michael L Cuccaro, John R Gilbert, Jonathan L Haines, Margaret A Pericak-Vance Molecular Autism 2011, 2:1 (19 January 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

12.

487
Accesses

Research   Open Access Highly Accessed

Intranasal oxytocin versus placebo in the treatment of adults with autism spectrum disorders: a randomized controlled trial

Evdokia Anagnostou, Latha Soorya, William Chaplin, Jennifer Bartz, Danielle Halpern, Stacey Wasserman, A Ting Wang, Lauren Pepa, Nadia Tanel, Azadeh Kushki, Eric Hollander Molecular Autism 2012, 3:16 (5 December 2012)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

13.

455
Accesses

Research   Open Access

Enzymes in the glutamate-glutamine cycle in the anterior cingulate cortex in postmortem brain of subjects with autism

Chie Shimmura, Katsuaki Suzuki, Yasuhide Iwata, Kenji J Tsuchiya, Koji Ohno, Hideo Matsuzaki, Keiko Iwata, Yosuke Kameno, Taro Takahashi, Tomoyasu Wakuda, Kazuhiko Nakamura, Kenji Hashimoto, Norio Mori Molecular Autism 2013, 4:6 (26 March 2013)

Abstract | Full text | PDF | PubMed

14.

413
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Research   Open Access Highly Accessed

Facial phenotypes in subgroups of prepubertal boys with autism spectrum disorders are correlated with clinical phenotypes

Kristina Aldridge, Ian D George, Kimberly K Cole, Jordan R Austin, T Nicole Takahashi, Ye Duan, Judith H Miles Molecular Autism 2011, 2:15 (14 October 2011)

Abstract | Full text | PDF | PubMed |  Editor’s summary

A distinctive facial phenotype in boys with autism, which differs from that of typically developing boys, may reflect alterations in embryologic brain development in children with autism spectrum disorders.

15.

354
Accesses

Research   Open Access

Task-related functional connectivity in autism spectrum conditions: an EEG study using wavelet transform coherence

Ana Catarino, Alexandre Andrade, Owen Churches, Adam P Wagner, Simon Baron-Cohen, Howard Ring Molecular Autism 2013, 4:1 (12 January 2013)

Abstract | Full text | PDF | PubMed

16.

333
Accesses

Research   Open Access

MeCP2 modulates gene expression pathways in astrocytes

Dag H Yasui, Huichun Xu, Keith W Dunaway, Janine M LaSalle, Lee-Way Jin, Izumi Maezawa Molecular Autism 2013, 4:3 (25 January 2013)

Abstract | Full text | PDF | PubMed

17.

330
Accesses

Research   Open Access

Lack of association of rare functional variants in TSC1/TSC2 genes with autism spectrum disorder

Samira Bahl, Colby Chiang, Roberta L Beauchamp, Benjamin M Neale, Mark J Daly, James F Gusella, Michael E Talkowski, Vijaya Ramesh Molecular Autism 2013, 4:5 (20 March 2013)

Abstract | Full text | PDF | ePUB | PubMed

18.

306
Accesses

Short report   Open Access

Evidence of reactive oxygen species-mediated damage to mitochondrial DNA in children with typical autism

Eleonora Napoli, Sarah Wong, Cecilia Giulivi Molecular Autism 2013, 4:2 (25 January 2013)

Abstract | Full text | PDF | PubMed

19.

289
Accesses

Review   Open Access Highly Accessed

Fragile X and autism: Intertwined at the molecular level leading to targeted treatments

Randi Hagerman, Gry Hoem, Paul Hagerman Molecular Autism 2010, 1:12 (21 September 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

20.

288
Accesses

Research   Open Access

Support for calcium channel gene defects in autism spectrum disorders

Ake Tzu-Hui Lu, Xiaoxian Dai, Julian A Martinez-Agosto, Rita M Cantor Molecular Autism 2012, 3:18 (15 December 2012)

Abstract | Full text | PDF | PubMed

21.

275
Accesses

Review   Open Access Highly Accessed

Review of neuroimaging in autism spectrum disorders: what have we learned and where we go from here

Evdokia Anagnostou, Margot J Taylor Molecular Autism 2011, 2:4 (18 April 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

22.

276
Accesses

Research   Open Access Highly Accessed

Histopathologic characterization of the BTBR mouse model of autistic-like behavior reveals selective changes in neurodevelopmental proteins and adult hippocampal neurogenesis

Diane T Stephenson, Sharon M O'Neill, Sapna Narayan, Aadhya Tiwari, Elizabeth Arnold, Harry D Samaroo, Fu Du, Robert H Ring, Brian Campbell, Mathew Pletcher, Vidita A Vaidya, Daniel Morton Molecular Autism 2011, 2:7 (16 May 2011)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central

23.

268
Accesses

Short report   Open Access

Prenatal versus postnatal sex steroid hormone effects on autistic traits in children at 18 to 24 months of age

Bonnie Auyeung, Jag Ahluwalia, Lynn Thomson, Kevin Taylor, Gerald Hackett, Kieran J O’Donnell, Simon Baron-Cohen Molecular Autism 2012, 3:17 (11 December 2012)

Abstract | Full text | PDF | PubMed

24.

262
Accesses

Research   Open Access

Identification of rare X-linked neuroligin variants by massively parallel sequencing in males with autism spectrum disorder

Karyn Steinberg, Dhanya Ramachandran, Viren C Patel, Amol C Shetty, David J Cutler, Michael E Zwick Molecular Autism 2012, 3:8 (28 September 2012)

Abstract | Full text | PDF | PubMed

25.

254
Accesses

Research   Open Access

Defining the broader, medium and narrow autism phenotype among parents using the Autism Spectrum Quotient (AQ)

Sally Wheelwright, Bonnie Auyeung, Carrie Allison, Simon Baron-Cohen Molecular Autism 2010, 1:10 (17 June 2010)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central |  Editor’s summary

The Autism Spectrum Quotient self-report questionnaire can be used to assess the broader, medium and narrow autism phenotypes in non-clinical samples, including first-degree relatives of individuals with autism spectrum conditions.

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