Table 1

Genes showing >2fold change at P< 0.05 in 39,XY*O whole brain based on the microarray analysis
Upregulated in 39,XY*O brain
Gene Chromosome Product Fold change P-value Human orthologue
Gm16432 1 Function unknown 5.5 0.006 None
Vmn2r86 10 Vomeronasal 2 receptor 86 3.6 0.03 None
Sfi1 11 Sfi1 homolog, spindle assembly associated (yeast) 3.3 0.007 SFI1 (22q12.2)
Pisd-ps1 11 Phosphatidylserine decarboxylase, pseudogene 1 2.7 0.02 None
Tagap1 17 T cell activation GTPase activating protein 1 2.4 0.01 None
C1qc 4 Complement component 1, q subcomponent, C chain 2.3 0.002 C1QC (1p36.11)
Fam177a 12 Family with sequence similarity 177, member A 2.2 0.004 FAM177A1 (14q13.2)
Metap1d 2 Methionyl aminopeptidase type 1D 2.0 0.0003 METAP1D (2q31.1)
Downregulated in 39,XY*O brain
Gene Chromosome Product Fold change p-value Human orthologue
Erdr1 Y Erythroid differentiation regulator 1 3.6 1.3x10−6 None
Trdn 10 Triadin 3.1 0.03 TRDN (6q22.31)
Gm12696 4 Pseudogenic RNA 2.9 0.01 None
Fut11 14 Fucosyltransferase 11 2.2 0.002 FUT11 (10q22.2)
AA388235 17 Non-coding RNA 2.1 0.03 None

Trent et al.

Trent et al. Molecular Autism 2014 5:21   doi:10.1186/2040-2392-5-21

Open Data