Figure 7.

Analysis of ubiquitin ligase 3A (UBE3A) and GABAA receptor β3 (GABRB3) protein levels in postmortem human brain samples. Box-and-whisker plots diagramming protein levels in postmortem human brain tissue normalized to glyceraldehyde 3-phosphate dehydrogenase (GAPDH) by Western blot analysis with a significant increase of UBE3A protein level in duplication of 15q11-q13 (dup15q) (a) and no significant change in GABRB3 protein levels (b). Significant differences are indicated by *P < 0.05 and **P < 0.01. Significant differences in the group means were determined by t-test. Distribution histograms of protein levels of individual brain tissue samples are shown in Additional file 7.

Scoles et al. Molecular Autism 2011 2:19   doi:10.1186/2040-2392-2-19
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