Table 3 |
|||||||||
|
Results for SNPs with replication and meta- and joint analysis P values < 0.05 and within candidate genes or regions |
|||||||||
|
Marker |
Map position (bp) |
Minor/major allele |
MAFa |
Discovery |
Validation |
Meta |
Joint |
Test |
Gene |
|
|
|||||||||
|
rs721699 |
32,468,253 |
T/C |
0.384 |
7.45 × 10-3 |
4.72 × 10-2 |
9.57 × 10-4 |
5.70 × 10-4 |
Overall |
DMD |
|
rs9887672 |
104,882,811 |
T/C |
0.103 |
2.17 × 10-2 |
1.53 × 10-3 |
1.28 × 10-4 |
1.20 × 10-3 |
Male |
IL1RAPL2 |
|
rs10218388 |
104,875,605 |
C/T |
0.107 |
3.08 × 10-2 |
2.64 × 10-3 |
2.94 × 10-4 |
2.5 × 10-4 |
Male |
IL1RAPL2 |
|
rs5962575 |
104,868,160 |
C/T |
0.107 |
3.44 × 10-2 |
2.19 × 10-3 |
2.86 × 10-4 |
2.30 × 10-4 |
Male |
IL1RAPL2 |
|
|
|||||||||
|
aMinor allele frequency (MAF) estimated on the basis of the discovery data set. DMD = Dystrophin Duchenne muscular dystrophy gene; IL1RAPL2 = IL-1 receptor accessory protein-like 2 gene. |
|||||||||
|
Chung et al. Molecular Autism 2011 2:18 doi:10.1186/2040-2392-2-18 |
|||||||||
