Table 4

Pearson correlation coefficients of cytokines measured in maternal midpregnancy serum in the Early Markers for Autism studya

Measurements

ASD (N = 84

ASD regression (N = 17)

Early-onset ASD (N = 64)

ASD with ID (N = 34)

ASD without ID (N = 30)

DD (N = 49)

GP (N = 159)


Cytokines elevated in ASD

IFN-γ and IL-4

0.95**

0.95**

0.81**

0.98**

0.97**

0.05

0.48**

IFN-γ and IL-5

0.73**

0.97**

0.55**

0.91**

0.87**

-0.07

0.38**

IL-4 and IL-5

0.72**

0.89**

0.83**

0.97**

0.82**

0.41**

0.77**

Cytokines elevated in DD

IL-2 and IL-4

0.87**

0.72**

0.62**

0.97**

0.78**

0.57**

0.43**

IL-2 and IL-6

0.02

0.34

0.18

-0.06

0.34

-0.15

0.24**

IL-4 and IL-6

0.15

0.46

0.34*

-0.09

0.42*

0.13

0.11


aASD: autism spectrum disorder; ID: intellectual disability; DD: developmental delay; GP: general population. **P < 0.0001, *P < 0.05.

Goines et al. Molecular Autism 2011 2:13   doi:10.1186/2040-2392-2-13

Open Data