Table 6 |
||||
|
Power analysis referring to a family-based design for rare variants with high penetrance and a dominant model. |
||||
|
Allele frequency |
Penetrance |
Power |
||
|
|
||||
|
AA |
AB |
BB |
||
|
|
||||
|
0.10 |
0.8 |
0.8 |
0.0 |
1.000 |
|
|
||||
|
0.08 |
0.8 |
0.8 |
0.0 |
1.000 |
|
|
||||
|
0.06 |
0.8 |
0.8 |
0.0 |
1.000 |
|
|
||||
|
0.04 |
0.8 |
0.8 |
0.0 |
0.986 |
|
|
||||
|
0.02 |
0.8 |
0.8 |
0.0 |
0.642 |
|
|
||||
|
0.01 |
0.8 |
0.8 |
0.0 |
0.075 |
|
|
||||
|
0.10 |
0.9 |
0.9 |
0.0 |
1.000 |
|
|
||||
|
0.08 |
0.9 |
0.9 |
0.0 |
1.000 |
|
|
||||
|
0.06 |
0.9 |
0.9 |
0.0 |
1.000 |
|
|
||||
|
0.04 |
0.9 |
0.9 |
0.0 |
0.998 |
|
|
||||
|
0.02 |
0.9 |
0.9 |
0.0 |
0.767 |
|
|
||||
|
0.01 |
0.9 |
0.9 |
0.0 |
0.144 |
|
|
||||
|
0.10 |
1.0 |
1.0 |
0.0 |
1.000 |
|
|
||||
|
0.08 |
1.0 |
1.0 |
0.0 |
1.000 |
|
|
||||
|
0.06 |
1.0 |
1.0 |
0.0 |
1.000 |
|
|
||||
|
0.04 |
1.0 |
1.0 |
0.0 |
0.999 |
|
|
||||
|
0.02 |
1.0 |
1.0 |
0.0 |
0.751 |
|
|
||||
|
0.01 |
1.0 |
1.0 |
0.0 |
0.146 |
|
|
||||
|
Muscarella et al. Molecular Autism 2010 1:9 doi:10.1186/2040-2392-1-9 |
||||
