Table 2

Descriptive information for pedigree subjects.

Mean ADI domain scores (SD; N)


Diagnostic group

N

Male: female

IQ > 70 (%)

Mean age (SD)

Mean SRS score (SD; N; % child version)

Social

Verbal

Non-verbal

Restr/

Repet


Autism*

135

119:16 (7.44:1)

69/125 (55.2)

13.87 (11.44)

107.0 (31.4; N = 126; 75.4%)

21.8 (6.4)

17.2 (4.7)

12.3 (2.3; N = 26)

6.7 (2.6)


ASD†

46

36:10 (3.60:1)

37/43 (86.1)

16.98 (15.25)

86.4 (29.1; N = 41; 75.6%)

12.7 (5.9)

10.5 (6.4)

(N = 0)

5.3 (2.9)


All affected subjects

181

155:26 (5.96:1)

106/168 (63.1)

14.64 (12.51)

101.9 (33.5; N = 167; 75.5%)

19.5 (7.5)

15.2 (6.1)

12.3 (2.3; N = 26)

6.3 (2.7)


All relatives with no ASD diagnosis

448

211:237(0.9:1)

37.30 (20.49)

28.7 (24.0; N = 351; 22.5%)


* 11 cases were missing an Autism Diagnostic Interview (ADI); five cases were missing an Autism Diagnostic Observation Schedule.

Three cases were missing an ADI; no cases were missing an ADOS.

SD, standard deviation; SRS, Social Responsiveness Scale; Restr/Repet, Restricted Interests/Repetitive Behaviors Domain Score

Coon et al. Molecular Autism 2010 1:8   doi:10.1186/2040-2392-1-8

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