Table 3 |
|||||
|
Case-control genotype-based test results. |
|||||
|
SNP |
Population |
Model |
OR |
CI |
P-value |
|
|
|||||
|
rs10261004 |
Northern Dutch |
Additive G |
0.44 |
(0.26, 0.75) |
3.00E-03 |
|
rs10261004 |
Northern Dutch |
TT versus GG/GT |
2.42 |
(1.33, 4.41) |
4.00E-03 |
|
rs1998753 |
Northern Dutch |
Additive G |
0.10 |
(0.05, 0.20) |
5.68E-12 |
|
rs1998753 |
Northern Dutch |
AG versus GG/AA |
9.64 |
(5.06, 18.38) |
5.68E-12 |
|
rs17279006 |
Overall |
Additive G |
0.62 |
(0.45, 0.84) |
2.22E-03 |
|
rs17279006 |
Overall |
AA versus GG/AG |
1.65 |
(1.19, 2.29) |
2.59E-03 |
|
rs17279006 |
Multiplex (IMGSAC) |
AA versus GG/AG |
2.14 |
(1.28, 3.59) |
3.96E-03 |
|
rs17279006 |
Multiplex (IMGSAC) |
Additive G |
0.49 |
(0.30, 0.79) |
4.00E-03 |
|
rs1925613 |
Overall |
CC versus AA/AC |
1.81 |
(1.37, 2.39) |
2.97E-05 |
|
rs1925613 |
Overall |
Additive C |
1.35 |
(1.16, 1.57) |
7.82E-05 |
|
rs1925613 |
Singleton (IMGSAC) |
CC versus AA/AC |
3.01 |
(1.66, 5.47) |
2.81E-04 |
|
rs1925613 |
Singleton (IMGSAC) |
Additive C |
1.80 |
(1.27, 2.54) |
8.97E-04 |
|
rs10997482 |
Overall |
Additive G |
1.38 |
(1.20, 1.60) |
9.81E-06 |
|
rs10997482 |
Overall |
GG versus AA/AG |
1.60 |
(1.27, 2.00) |
4.63E-05 |
|
rs10997482 |
Singleton (IMGSAC) |
Additive A |
0.54 |
(0.38, 0.77) |
6.85E-04 |
|
rs10997482 |
Singleton (IMGSAC) |
GG versus AA/AG |
2.41 |
(1.45, 4.03) |
7.45E-04 |
|
rs2619652 |
Overall |
Additive T |
0.76 |
(0.67, 0.88) |
1.57E-04 |
|
rs2619652 |
Overall |
TT versus CC/CT |
0.63 |
(0.49, 0.81) |
2.71E-04 |
|
rs2619652 |
Singleton (IMGSAC) |
Additive T |
0.58 |
(0.41, 0.82) |
1.95E-03 |
|
rs2619652 |
Singleton (IMGSAC) |
TT versus CC/CT |
0.34 |
(0.17, 0.69) |
2.56E-03 |
|
rs10740268 |
Overall |
TT versus CC/CT |
0.51 |
(0.38, 0.70) |
2.16E-05 |
|
rs10740268 |
Overall |
Additive C |
1.84 |
(1.38, 2.45) |
3.48E-05 |
|
rs12785206 |
Overall |
TT versus CC/CT |
1.49 |
(1.20, 1.86) |
3.96E-04 |
|
rs12785206 |
Singleton (IMGSAC) |
CC/CT versus TT |
0.37 |
(0.22, 0.65) |
4.20E-04 |
|
rs12785206 |
Singleton (IMGSAC) |
Additive C |
0.48 |
(0.31, 0.74) |
1.00E-03 |
|
|
|||||
|
Only the most significant results are shown (P < 0.005). SNP, single nucleotide polymorphism; OR, odds ratio; CI, confidence interval. |
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|
Sousa et al. Molecular Autism 2010 1:7 doi:10.1186/2040-2392-1-7 |
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